Based on specific chemical markers of microorganisms more than 50 childbirth/species of microorganisms of a small intestine of the person was defined in blood of donors and elderly people. The analysis of patterns of microbiota of small intestine revealed existence of both big interindividual variations in specific structure of microorganisms, and significant intergroup distinctions in structure and quantity of microorganisms between groups of young and elderly individuals, and between groups of people of advanced age with the different psychophysical status. For elderly people with the expressed psychophysical insufficiency microbic patterns of small intestine with the high maintenance of "patobiont", such as Enterococcus spp and Staphylococcus aureus are characteristic in comparison with people of advanced age with moderate cognitive frustration and insignificant physical violations.

This paper is devoted to assessing the prevalence of different haplotypes in toll-like receptor genes in Chelyabinsk Region populations. Here is examined gene cluster TLR10–TLR1–TLR6, containing single nucleotide polymorphisms, effected by natural selection during development of human world populations. Differences in the frequency of certain three-locus haplotypes in populations of Russians, Bashkirs and Nagaybaks of Chelyabinsk Region are demonstrated.

The relevance of the investigated problem is caused by a significant role in the functioning of the human body adaptation mechanisms of the cardiovascular system and, related to this, the need to expand the arsenal of diagnostic methods of its states, including - using a systematic approach to the registration of parameters is relatively easy to measure. The purpose of the article is to study the structure of relationships in normal and pathological indicators such as heart rate, systolic and diastolic blood pressure, total peripheral vascular resistance. The leading method to the study of this problem is a formalized description of this structure with the help of a new class of mathematical models, known as discrete models of dynamic systems - DMDS. The results show significant differences articles loops and destructive deviation in the iconic graphs describing the structure of the relations of the above parameters of the cardiovascular system in health and disease, which in turn determines the nature of their role in the dynamics and adaptive mechanisms of the human body. Article Submissions may be useful to extend the concepts of systemic aspects of the functioning of the cardiovascular system in health and disease, and in practical terms, to create information systems monitor the status of adaptation mechanisms of the human body.

The relevance of the investigated problem is caused by the occurrence of cognitive impairment resulting from cerebrovascular disorders on the background of stress complex interpersonal relationship between two people, manifested in the form of a family crisis. The purpose of the article is to identify the factors leading to interpersonal and family crises. The leading method are the methods of statistical data and in particular the criterion of Kruskal-Uolissa. The study revealed the factors that most influence the interpersonal relationships in the family. The article submissions may be useful to detect cerebrovascular disorders and states of crisis in family relationships.

The relevance of the investigated problem is caused by the increase of morbidity and mortality from cardiovascular disease people of working age. The goal of the theses is aimed at solving the problem of determining the survival rate of patients after myocardial infarction. The leading method of research of this problem is the method of Cox.

The article presents the original algorithm and software for complex research and energy parameters in the hydrostatic bearing (GSP), compiled in MATLAB package. The analysis of the frequency characteristics of the automatic control system (ACS) for roughing and finishing modes spindle unit (SHU). The conclusions about the impact of regimes on the dynamic quality of ATS GSP.

This paper tells us about the use of different exercises and methods showing the Russian area studies in English and that will facilitate the patriotic component use within the program of English in non-linguistic universities.

The paper is devoted to Russian novel as a specific narrative form of discourse, analogies, particularly flexible model that can be used to explain phenomena by reference to the rules, including generalized knowledge. Special attention [s given to the novel "Eugene Onegin" by A.S. Pushkin. "Eugene Onegin" has the optimal shape of the distribution on the semantic plane and its linguistic forms represent the Russian verbal culture . "Modern Russian language" crested by A.S. Pushkin is researched from positions of Radical constructivism.

The paper deals with the area cultural studies while teaching of Russian as a second language. The topic “The cultural life of the Kuban Land” is considered as an example. Particular attention is paid to an educational tour as one of the most efficient ways of gaining cultural information.

The paper is devoted to studying literature as an element of education and training Russian nobility, it draws attention to the role of ancient authors in shaping the world of young people of the upper class.

The history of law enforcement agencies can not be adequately covered without the analysis of the development of similar structures in the territories occupied by the White armies. This article discusses the period of liquidation of the White Czechs Soviet law enforcement agencies of the Tyumen region, covers the activities of the counter-revolutionary Provisional Siberian Government in the region to restore law and order in the territory under the control of, analyzes the structure and function of the police in the region, formed in the period of the Provisional Siberian Government and the Government of the Kolchak.

Investigating the functioning of knowledge and information in the process of cognition, the author reaches conclusion that knowledge as a content of intelligence is a result of subjectivizing of patterns, extracted from information as content of the surrounding validity – nature and sociocultural reality.

The paper is devoted to the analysis of specific conditions of genesis of the identity of inhabitants of a small country town of the Vologda region from the social and philosophical point of view. Applying dialectic and system methods, the author reveals the inconsistent conditions of an urban environment having impact on formation of the personality; comes to a conclusion about existence of mass of the factors limiting development of the identity of the provincial.

The basic elements of civil society, and their significance. It emphasizes the particular importance of ideological diversity and freedom of information as the main determinants influencing the surge of ethnic and religious intolerance. Revealed the imperfection of the current legislation, argued for the problems arising in the field of public relations. The ways of solving this problem.

The paper reports about current diversification trends in Russian construction industry. There are analyzed diversification and integration types of the largest Russian construction companies. The author concludes which strategy is the most popular and effective.

The urgency of the research problem causes to lack of a unified methodology for assessing the risk to human health in different environments. The article aims to analyze the known methods of health risk assessment. The leading approach to the study of this problem is the method, which underlies the foreign methods, involves the calculation of doses of substances entering the human body. Article`s data may be useful to researchers who are developing new approaches of risk assessment or directly in conducting this assessment.

In the paper, the author examines the main theories of the European economic integration, as well as their correlation with the economic situation nowadays. The research describes the current condition of the integration processes in the European Union, in line with the analysis of conceptual intersection of main ideas in these theories. Additionally, the author analyses the reasons for the euro-scepticism and makes the conclusion about a strong influence of neofunctionalism.

Problems of market segmentation methodology are considered in article. It is shown that on this method in scientific works there is no uniform classification of methods of segmentation, and signs for drawing up similar classification are offered. Further methods of segmentation are described and their features are considered. Such approach allows marketing specialists to choose the most suitable method of market segmentation in each concrete situation.

The paper deals with tendencies of structure and movement of fixed assets in the agricultural enterprise. The author presents the results of the economic research of fixed assets and their influence on financial condition of the enterprise. Dynamics of indicators of their effective use is analyzed. The presented recommendations about acceleration of stocks turnover can find practical application in registration and analytical activity of the agricultural enterprise.

Modern enterprise management is carried out both at the operational and strategic levels. Therefore, organizational and economic management decisions that determine the flow of resources at the operational level, must implement the strategic concept and installation. Administrative decisions on resources Multivariate Thus, we need coordinated decisions on the volume and timing of release, updating the product range, supply, financing and replacement of technological equipment. Therefore, in the present conditions it is necessary to optimize management decisions in relation to the system of material and credit - monetary resources of the enterprise at the organizational level by economic criteria, taking into account resource constraints so that the operational management of the resources of the system performs adequately with the strategic objectives of the enterprise.

The paper deals with characterological features of adult learners from the position of andragogical approach. It argued the use of the "portfolio" as modern educational technology in the results presentation of teaching-and-learning activities in the system of additional vocational education. It is proposed the structure of a thematic "portfolio" for training courses.

The present paper is aimed at showing the author’s opinion about one more way to avoid subjectivity in the assessment process and to improve pedagogical interaction between lecturers and students.

Communicative approach focuses on formation of skills of speech activity, i.e. skills of constructing verbal statements or chain of utterances. In other words, it is about the development of students' lexical, grammatical and phonetic skills as a psychological component of foreign language in writing and speaking. The communicative approach involves the assimilation of a foreign language directly in the function of communication. Communicative competence means the ability to work together with other people, knowledge of psychology and ethics and the ability to an accurate perception of other person. When constructing a model of communicative competence special attention should be paid to its components. The division of all the components of the model of communicative competence into structural and functional is logical and quite natural. The list of communicative qualities may vary in any range depending on the number of subjective and objective factors. The essence of the communicative approach to language learning lies in creation of special circumstances in the process of training sessions in which the learner basing on the acquired knowledge independently solves communicative tasks by means of a foreign language in the process of communication or in the process of finding solutions when reading literature. In this case reliance is placed on the technique of learning through active methods and motivation development to form foreign language communicative competence of the learner. Discussing the types of speech activity at foreign language lessons (speaking, listening, reading, writing) it should be noted that teaching has to be communicative oriented. All these kinds of speech activity should be presented in special communicative exercises. Under communicative exercise, we can understand the performance of students of certain repetitive actions aimed at the production (formation) of their communicative skills for their professional life. The scope and nature of the exercises depend on several factors. There is no urgent need to use all types of exercises in each session and in relation to each type of speech activity. Each stage of training must meet certain communicative exercises that stimulate the students’ speech. In conclusion, we can say that nowadays the communicative method of teaching foreign languages is considered to be the most effective.

The authors give grounds for the necessity of implementing civic and informational paradigm and molding civic consciousness. The relevance of this approach is determined by developing civic consciousness of modern labor relations’ participants, it is associated with the transition to civil information educational paradigm that gives students the opportunity to work and communicate effectively. The article presents the results of the research, organized to find out the university staff attitude towards human and civil values. The received data prove that the educators realize the importance of civic education and are personally prepared to develop civic consciousness in students.

The relevance of the problem is caused by the need of ensuring national security, which is under the threat due to the developed problems in political, social, technological and ecological spheres. The paper is directed on illumination of the possible solution of the problem, which essence is increase the level of health-safety culture. The problem is viewed within Perm National Research Polytechnic University (PNRPU). The research of the specified pedagogical problem help to conclude that there is a need of complex use of such modern approaches as system, activity, personal focused, axiological, reflexive and cultural. As the result, the author developed methodological bases for creation the continuous education system in the sphere of health and safety at polytechnic higher educational institution. The paper can be useful to graduate students, undergraduates, doctoral candidates, educators for solution the problem of increase of students’ health-safety culture.

The article highlighted one of the main causes of accidents and man-made disasters. The authors reviewed and analyzed by the Federal State Educational Standard 20.03.01 directions to the expert, oversight and inspection and audit activities. In order to clarify the direction of the educational program "Technosphere safety", the authors offered professional tasks, professional competence and expertise distsiplinydlya, supervision and inspection and audit activities.

The article is devoted to one of the topical issues in the problem of the teacher professional field associated with the assessment of his professional competences. The results of experimental work on the assessment of professional competence of the teacher, identified on the basis of the analysis of the new context of his professional activity.

Elements of the developed concept of formation of humanistic culture of students. First presented scientifically sound understanding of the process of formation of student humanist culture as purposeful process of moral education and training, as part of the general culture of the individual. The authors have developed a new methodological approach to pedagogical process of formation of humanistic culture, which includes principles, methods, criteria for determining the level of the individual student's humanistic culture. A study conducted in VPO «Perm State Academy of Art and Culture.

The article describes the main directions and results of the "Dobrograd-1" student activities Science Laboratory, set up at the Department of natural and mathematical sciences and their methodology of teaching in pre-school and primary education in the VPO "Adygeya State University." We consider the planned and implemented target indicators in the research work of students of 1-2 courses of the Faculty of Pedagogy and Psychology.

The article considers one of the approaches to the use of pedagogical designing in working with preschool teaching staff as a means of development of communicative competence of teachers. The author draws a parallel between "design" and "communicative competence". The variant of the use of this form of organization of methodical work as the festival of educational projects in order to improve the components of communicative competence of the modern teacher.

The authors consider the problem of tolerance in today's multicultural society. According to the article the need of formation of culture of tolerance due to the involvement of Russian educational institutions in the Bologna process and the expansion of inter-ethnic contacts. However, the installation of the federal law on education in Russia consists in the fact that the content of education should promote interaction and cooperation between people on the basis of teaching students tolerance, which is an integral part of the general culture and citizenship, is not reflected in the work programs of the humanities disciplines. The above analysis of the authors of studies on the issue of tolerance leads to the conclusion that the level of students' culture of tolerance is not enough formed and there is a need of special training and orientation of the educational process on the formation of a culture of tolerance.

This article presents some results of the andragogical model of mentoring in which subjects observed parity mentoring to overcome the deficiencies of the professional competencies of each other.

The purpose of the study is to create approaches to use in teaching practice tools that allow high school students to attach effectively to the study of technical systems and, as a consequence, to create conditions for their creative solutions (inventive) tasks. The basic approach to training professional technical creativity is occupying a special place in Russian Theory of Inventive Problem Solving (TRIZ) by G. Altshuller; due to the complexity and difficulty of use in the educational process based on it created a simplified algorithm of inventive problem solving, among which we have selected a block diagram of solving creative problems "generator of ideas" S. Malkin, based on the part of the algorithm of Inventive Problem Solving (ARIZ). Article Submissions are of practical value to teachers of the primary and secondary education students involved in the development of technical creativity of pupils, as well as for all those who are in creative search of new opportunities in the field of self-development of technical systems.

This paper deals with the research of the state of institution of foster family in the Republic of Adygheya (Russian Federation). The study represents the results of monitoring research of the effectiveness of foster family as a form of placement of orphans and children who are left without parental charge.

The paper is devoted to a question of formation of second-graders’ cogitative operations in the course of studying geometrical material. The author analyzes the main types of cogitative operations and features of studying geometrical material in the 2nd grade. Based on the empirical research on the problem the author reveals the efficiency of conditions of cogitative operations development among second-graders in the course of studying geometrical material. The developing tasks for fixing knowledge and abilities on geometry subjects are presented.

The aim of this study was to analyze the effectiveness of psychocorrectional effects in asthma. 141 patients was examined with asthma. Assessed alexithymia level and the level of asthma control in patients. On the part of the psycho patient work we developed the scheme was carried out. It is shown that psycho work with patients increases the effectiveness of standard therapies. The foregoing is the rationale for inclusion of psychological correction in the complex therapy of bronchial asthma.

The article is devoted to study the essence of adaptive capacity and psychological well-being. The author presents a theoretical analysis of modern views on adaptation potential, considering the basic views on the problem of psychological well-being and describes the results of empirical research of the relationship of components adaptive capacity of the individual and psychological well-being levels.

At present, computer technologies, such as multimedia presentations, play an important role in the education of children with disabilities, which act as a powerful and effective means of corrective action. Computer technologies are included in the structure of conventional speech therapy classes in remedial schools and classes for individual learning of children with mental retardation.

The article describes the impact of extracurricular activities on the formation of spiritual and moral culture of primary school pupils. Extracurricular activity allows us to givestudents an opportunity to express themselves in the field of fine art, to form artistic culture, which is an integral part of the spiritual culture.